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The patient was treated with methylprednisolone, cyclosporin and mycophenolate mofetil, with a partial response diarrhea and abdominal pain improved , but then he developed multiple other medical complications and died after 3 months. Clinical manifestations of gut GVHD include diarrhea, nausea, vomiting and crampy abdominal pain. The gastrointestinal system is the third most common organ involved in acute GVHD. Broad-spectrum antibiotics and other supportive measures were begun and the patient was moved to the intensive care unit. Intestinal and hepatic complications of human bone marrow transplantation. Abstract Diffuse involvement of the gastrointestinal tract by graft versus host disease GVHD is a common complication of allogeneic hematopoietic stem cell transplant HSCT. The oral cavity showed features of mucositis.

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The pathophysiology of acute graft-versus-host disease.

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This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Stage 1 is normal appearing mucosa, stage 2 will show a loss of vascular marking of normal colonic vascular pattern or there will be focal mild erythema. Prognostic value of apoptotic cells and infiltrating neutrophils in graft-versus-host disease of the gastrointestinal tract in humans: TNF and Fas expression. Clinical manifestations of gut GVHD include diarrhea, nausea, vomiting and crampy abdominal pain.

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