CNN There's a surprising upside to the virus that causes polio disease, new research indicates. Chat with us in Facebook Messenger. Find out what's happening in the world as it unfolds.
I have joined Post-Polio Health International and would like to submit a question. I am a year-old polio survivor who was diagnosed with breast cancer last year. I underwent a lumpectomy, chemotherapy, radiation therapy and my oncologist prescribed Aromacin for the next 5 years.
Describing this process in a paper published Sept. The modified poliovirus received a breakthrough therapy designation from the Food and Drug Administration last year, expediting research. Knowing the steps that occur to generate an immune response will enable us to rationally decide whether and what other therapies make sense in combination with poliovirus to improve patient survival.
Food and Drug Administration. The designation will expedite research into the poliovirus therapy, but it does not mean the investigational drug has been approved for clinical use. It is currently being tested in a clinical trial for adults with advanced glioblastoma brain tumors. To receive breakthrough status, preliminary evidence must indicate that the treatment may offer substantial improvement over available standard therapy.
There's an exciting new breakthrough in treating some types of deadly brain tumors, that uses, of all things, a polio virus. Doctors at Duke Health in North Carolina genetically altered the virus because it produces such a strong immune response in our bodies. The result is a longer life for patients whose brain cancer returned.
Poliomyelitis is an acute highly contagious infection caused by polioviruses, a positive stranded RNA virus from the genus Enterovirus. Polioviruses are able to remain in the soil and water for weeks, and they have a high recombination capacity. Poliomyelitis should be suspected in any child or adolescent presenting with fever, headache, muscle aches and acute onset weakness.
Vaccines are the shining example of using bad bugs to do good in priming the immune system to fight disease. There is only one approved virus-based treatment for cancer, which uses herpes virus against melanoma. In a new report published in the New England Journal of Medicinehowever, scientists led by a team at Duke University report they may have trained another virus to target cancer, by using poliovirus to target brain tumors.
Matthias Gromeier holds a sample of the modified poliovirus he developed which attacks glioblastoma brain tumor cells. Describing this process in a paper published Sept. The modified poliovirus received a breakthrough therapy designation from the Food and Drug Administration last year, expediting research.
Rob Stein. Poliovirus, long a scourge, has been modified by Duke University researchers for experimental use as a brain cancer treatment. A genetically modified poliovirus may help some patients fight a deadly form of brain cancer, researchers report. The experimental treatment seems to have extended survival in a small group of patients with glioblastoma who faced a grim prognosis because standard treatments had failed, Duke University researchers say.